Revvity Phospho-AMPK (Thr172) cellular kit, 50000 Tests

Revvity 5 AMP-activated protein kinase (AMPK) is considered the metabolic master switch. AMPK is activated by phosphorylation on Thr172 by CaMKK2 and LKB1, among others. Upon activation, it inhibits synthesis of fatty acids, cholesterol, and triglycerides, and activates fatty acid uptake and ?-oxidation as well as stimulating glucose uptake. AMPK is also involved in autophagy activation through direct phosphorylation of ULK1. Cisbios cell-based homogeneous HTRF kit for phospho-AMPK (Thr172) enables the quantitative detection of AMP-activated protein Kinase modulation, phosphorylated at Threonine 172. - PEMSD (Additional S&H or Hazmat Fees May Apply)