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Revvity HTRF Human Phospho-JAK1 Tyr1034/1035 Detection K
List Price $45,526.00 Your Price $45,526.00
Revvity This HTRF kit enables the cell-based quantitative detection of phosphorylated JAK1 at Tyr1034/1035 as a readout of cytokine receptor activation. - PEMSD (Additional S&H or Hazmat Fees May Apply)
NETA PART: PEMSD-64JAK1Y10PEY
MFG.PART: 64JAK1Y10PEY
UNSPSC: 41106509
Manufacturer: Revvity
Revvity JAK1 (Janus kinase 1) belongs to the family of non-receptor Janus tyrosine kinases with JAK2, JAK3, and TYK2. A wide array of cytokines and growth factors ( IL6, IL4, IFNalpha, GM-CSF) attached to their receptors induce the phosphorylation of JAKs. The activated JAKs subsequently phosphorylate additional targets, including both the cytokine receptors and the major substrates: STATs. The JAKs/SATs signaling stimulates cell proliferation, differentiation, migration, and apoptosis. Altering JAK/Stat signaling to reduce cytokine induced pro-inflammatory responses represents an attractive target for anti-inflammatory therapies. - PEMSD
| SKU | PEMSD-64JAK1Y10PEY |
|---|---|
| Supplier Part Number | 64JAK1Y10PEY |
| UM | EA |
| UNSPSC | 41106509 |
| Manufacturer | Revvity |
| CountryOfOrigin | France |
| ProductLine | PEMSD |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 3.300000 |
| Lead Time | 4 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |