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Revvity HTRF Human Phospho-TYK2 Tyr1054/1055 Detection K
List Price $45,526.00 Your Price $45,526.00
Revvity This HTRF kit enables the cell-based quantitative detection of phosphorylated TYK2 at Tyr1054/1055, as a readout of cytokine receptor activation. - PEMSD (Additional S&H or Hazmat Fees May Apply)
NETA PART: PEMSD-64TYK2Y10PEY
MFG.PART: 64TYK2Y10PEY
UNSPSC: 41106509
Manufacturer: Revvity
Revvity TYK2 (Tyrosine kinase 2) belongs to the family of non-receptor Janus tyrosine kinases with JAK1, JAK2, and JAK3. A wide array of cytokines and growth factors (Interferons, IL12, IL23) attached to their receptors induce the phosphorylation of TYK2. The activated TYK2 subsequently phosphorylate additional targets, including both the cytokine receptors and the major substrates: STATs. The JAKs/STATs signaling stimulates cell proliferation, differentiation, migration, and apoptosis. Altering JAK/STATs signaling to reduce cytokine induced pro-inflammatory responses represents an attractive target for anti-inflammatory therapies. - PEMSD
| SKU | PEMSD-64TYK2Y10PEY |
|---|---|
| Supplier Part Number | 64TYK2Y10PEY |
| UM | EA |
| UNSPSC | 41106509 |
| Manufacturer | Revvity |
| CountryOfOrigin | France |
| ProductLine | PEMSD |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 3.300000 |
| Lead Time | 4 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |