Revvity AlphaLISA. SureFire Ultra. Human Phospho-Progesterone Receptor (Ser190) Detection Kit, 500 Assay Points

The Progesterone Receptor (PR) is a nuclear hormone receptor activated by the steroid hormone progesterone. PR regulates gene expression involved in reproductive tissue function, cellular differentiation, and proliferation. It exists in two isoforms, PR-A and PR-B, each with distinct and sometimes opposing roles in gene regulation. PR is a critical player in breast cancer development and is a target for endocrine therapies.

The AlphaLISA SureFire Ultra Human Phospho-Progesterone Receptor (Ser190) Detection Kit is a sandwich immunoassay for the quantitative detection of phospho-Progesterone Receptor (Ser190) in cellular lysates, using Alpha Technology.

Formats:

• The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 μL reaction volume.
• The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μL reaction volume.
• The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μL reaction volume.
• The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μL reaction volume.

AlphaLISA SureFire Ultra kits are compatible with:

• Cell and tissue lysates
• Antibody modulators
• Biotherapeutic antibodies

Alpha SureFire Ultra kits can be used for:

• Cellular kinase assays
• Receptor activation studies
• Screening