Revvity Citalopram, , 250µci (9.25mbq)

Revvity 250 µCi quantity of Citalopram, [N-Methyl-³H]-, is available for your research. Citalopram (Celexa, Cipramil) is a selective serotonin reuptake inhibitor (SSRI) that blocks the serotonin transporter (SERT, 5-HTT). Citalopram is used to treat panic disorder as well as obsessive-compulsive disorder. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity We offer both agonist and antagonist radioligands for autoradiographic visualization or performing saturation and competition assays to determine receptor expression levels (B_max), dissociation constants (K_d), association and dissociation rates (k_on and k_off), and inhibitor constants (K_i) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radioligands is fully characterized for pharmacological action and validated in receptor binding assays. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity Radiolabeled ligands remain the most sensitive method for probing receptor binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity References for NET1039: - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Pamela R. Tsuruda, Joey Yung, William J. Martin, Ray Chang, Ngoc Mai, Jacqueline A.M. Smith, Influence of ligand binding kinetics on functional inhibition of human recombinant serotonin and norepinephrine transporters, In Journal of Pharmacological and Toxicological Methods, Volume 61, Issue 2, 2010, Pages 192-204.Assié, M.-B. and Koek, W. [3H]-8-OH-DPAT binding in the rat brain raphe area: involvement of 5-HT1A and non-5-HT1A receptors. British Journal of Pharmacology, Volume 130, 2000, Pages 1348–1352.