Revvity HTRF Human Phospho-MET (Thr1234/1235) Detection Kit, 50,000 Assay Points

Revvity c-MET, also called tyrosine-protein kinase MET or hepatocyte growth factor receptor (HGFR), is a human MET gene-coded protein with tyrosine kinase activity. It acts as a tyrosine kinase receptor, with functions related to wound healing, organogenesis, and embryonic development. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity MET is expressed in epithelial cells and is triggered by hepatocyte factors HGF and HSF, with ramifications into various pathways like RAS-MAPK, AKT, and STAT3 signaling. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity Abnormal activation of MET is linked to cancer progression, with effects on tumor growth, angiogenesis, and tumor cell migration & invasion. These relationships between MET and tumor cells are found across multiple cancer types (liver, brain, breast, kidney, etc) and are suspected to originate from a hijacking of MET and its ligand expression regulation, which leads to their overexpression and autocrine activation of MET. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)