Revvity Propranolol, L--, 250µci (9.25mbq)

Revvity Propranolol is a beta blocker used to treat high blood pressure and irregular heart rate that acts as an antagonist at β1- and β2-adrenergic receptors. These receptors are involved in cardiac output and smooth muscle relaxation. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity We offer both agonist and antagonist radioligands for autoradiographic visualization or performing saturation and competition assays to determine receptor expression levels (B_max), dissociation constants (K_d), association and dissociation rates (k_on and k_off), and inhibitor constants (K_i) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radioligands is fully characterized for pharmacological action and validated in receptor binding assays. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity Radiolabeled ligands remain the most sensitive method for probing receptor binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity References for NET515: - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Hu, M., Zhou, T., Dezzutti C. S., and Rohan L. C. The Effect of Commonly Used Excipients on the Epithelial Integrity of Human Cervicovaginal Tissue. AIDS Research and Human Retroviruses. November 2016, 32(10-11): 992-1004.Morris, T.H. & Kaumann, A.J. Different steric characteristics of β1- and β2-adrenoceptors. Naunyn-Schmiedebergs Arch. Pharmacol. (1984) 327: 176.