Revvity Dihydroxyphenylethylamine, 3,4--, 250µci

Revvity 250 µCi quantity of Dihydroxyphenylethylamine, 3,4-[7-³H]-, is available for your research. Dihydroxyphenylethylamine binds dopamine receptors, a class of GPCRs in the central nervous system. Dopamine receptors are implicated in motivation, pleasure, cognition, memory, and learning and are potential drug targets for schizophrenia, Parkinsons disease, and a variety of other psychiatric and neurological conditions. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity We offer both agonist and antagonist radioligands for autoradiographic visualization or performing saturation and competition assays to determine receptor expression levels (B_max), dissociation constants (K_d), association and dissociation rates (k_on and k_off), and inhibitor constants (K_i) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radioligands is fully characterized for pharmacological action and validated in receptor binding assays. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity Radiolabeled ligands remain the most sensitive method for probing receptor binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity References for NET131: - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Oaks AW, Frankfurt M, Finkelstein DI, Sidhu A (2013) Age-Dependent Effects of A53T Alpha-Synuclein on Behavior and Dopaminergic Function. PLoS ONE 8(4): e60378.Oaks AW, Marsh-Armstrong N, Jones JM, Credle JJ, Sidhu A (2013) Synucleins Antagonize Endoplasmic Reticulum Function to Modulate Dopamine Transporter Trafficking. PLoS ONE 8(8): e70872.