Revvity AlphaLISA SureFire Biotin-Free Human and Mouse Phospho-Rb (Thr826) Detection Kit, 500 Assay Points

Revvity The retinoblastoma protein (Rb), encoded by RB1, is a tumor suppressor that regulates the cell cycle by inhibiting E2F transcription factors, thereby blocking S phase entry. Rb is inactivated via phosphorylation by cyclin-dependent kinases, enabling cell cycle progression. Mutations in RB1 cause retinoblastoma and are implicated in various cancers, including osteosarcoma and lung cancer, due to the loss of cell cycle control. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity The AlphaLISA SureFire Ultra Biotin-Free Human and Mouse Phospho-Rb (Thr826) Detection Kit is a sandwich immunoassay for the quantitative detection of phospho-Rb in cellular lysates, using Alpha Technology. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity Formats: - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 μL reaction volume.The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μL reaction volume.The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μL reaction volume.The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μL reaction volume.

Revvity AlphaLISA SureFire Ultra kits are compatible with: - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Cell and tissue lysatesAntibody modulatorsBiotherapeutic antibodies

Revvity AlphaLISA SureFire Ultra kits can be used for: - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Cellular kinase assaysReceptor activation studiesHigh-throughput screening for preclinical studies - REVPFZ (Additional S&H or Hazmat Fees May Apply)