Revvity AlphaLISA SureFire Biotin-Free Human and Mouse Phospho-STAT5 (Tyr694/699) Detection Kit, 500 Assay Points

Revvity STAT5, comprising STAT5A and STAT5B, is activated by JAK kinases in response to cytokine signaling. Upon phosphorylation, STAT5 forms dimers and translocates to the nucleus, inducing transcription of genes involved in proliferation, differentiation, and survival. Overactive STAT5 drives cancers like leukemia and breast cancer, while its dysregulation contributes to autoimmune diseases by promoting excessive immune responses. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity The AlphaLISA SureFire Ultra Biotin-Free Human and Mouse Phospho-STAT5 (Tyr694/699) Detection Kit is a sandwich immunoassay for the quantitative detection of phospho-STAT5 in cellular lysates, using Alpha Technology. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity Formats: - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 μL reaction volume.The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μL reaction volume.The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μL reaction volume.The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μL reaction volume.

Revvity AlphaLISA SureFire Ultra kits are compatible with: - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Cell and tissue lysatesAntibody modulatorsBiotherapeutic antibodies

Revvity AlphaLISA SureFire Ultra kits can be used for: - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Cellular kinase assaysReceptor activation studiesHigh-throughput screening for preclinical studies - REVPFZ (Additional S&H or Hazmat Fees May Apply)