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Revvity HTRF Human and Mouse Phospho-NPM1 Thr199 Detection Kit, 50,000 assay points
List Price
$42,189.00
Your Price
$42,189.00
Revvity HTRF Human and Mouse Phospho-NPM1 Thr199 Detection Kit, 50,000 assay points - REVPFZ (Additional S&H or Hazmat Fees May Apply)
NETA PART:
REVPFZ-64NPMT1PEY
MFG.PART:
64NPMT1PEY
UNSPSC:
41116126
Manufacturer:
Revvity
NPM1 (Nucleophosmin 1) is a molecular chaperone involved in cell cycle regulation, ribosome biogenesis, cell proliferation, DNA damage repair, and apoptosis. Its phosphorylation on Thr199 by the CDK2/Cyclin E complex regulates mitosis, centrosome duplication, pre-mRNA processing, and G2/M cell cycle arrest through its interaction with p53/MDM2.
NPM1 functions both as an oncogene and a tumor suppressor. It is frequently overexpressed, altered, and rearranged, or sporadically deleted in human cancers. NPM1 is also the most frequently mutated gene (NPM1c) in acute myeloid leukemia (AML).
- REVPFZ (Additional S&H or Hazmat Fees May Apply)| SKU | REVPFZ-64NPMT1PEY |
|---|---|
| Featured | No |
| Supplier Part Number | 64NPMT1PEY |
| UM | EA |
| UNSPSC | 41116126 |
| Manufacturer | Revvity |
| CountryOfOrigin | France |
| ProductLine | REVPFZ |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 1.500000 |
| Lead Time | 4 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |