Revvity AlphaLISA SureFire Biotin-Free Human and Mouse Total ERK1/2 Detection Kit, 500 Assay Points

Revvity Extracellular signal-regulated kinases 1/2 (ERK1/2) are central components of the MAPK signaling cascade, regulating cell growth, survival, and differentiation. Activated by MEK1/2 through phosphorylation, ERK1/2 phosphorylate diverse cytoplasmic and nuclear targets. ERK1/2 dysregulation is associated with cancer, driving tumor proliferation and resistance to therapy, and with neurodegenerative diseases like Alzheimers, where it influences amyloid plaque formation. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity The AlphaLISA SureFire Ultra Biotin-Free Human and Mouse Total ERK1/2 Detection Kit is a sandwich immunoassay for the quantitative detection of total ERK1/2 in cellular lysates, using Alpha Technology. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity Formats: - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 μL reaction volume.The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μL reaction volume.The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μL reaction volume.The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μL reaction volume.

Revvity AlphaLISA SureFire Ultra kits are compatible with: - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Cell and tissue lysatesAntibody modulatorsBiotherapeutic antibodies

Revvity AlphaLISA SureFire Ultra kits can be used for: - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Cellular kinase assaysReceptor activation studiesHigh-throughput screening for preclinical studies - REVPFZ (Additional S&H or Hazmat Fees May Apply)