Revvity PG-Seq Core Panel

The PG-Seq Core Panel analyzes over 200 SNPs located 2 Mb upstream and downstream of the gene or region of interest, covering a total of 4 Mb. Bioinformatics tools are employed to select SNPs with the highest probability of being informative. Additionally, full sequencing of the gene of interest is incorporated to facilitate direct analysis of the variants under study. Most of the pathogenic and likely pathogenic variants in splicing and UTR regions described on ClinVar are included.

Powered by Journey Genomics, the analysis software allows tracking of allele dropouts, recombination events and direct and indirect testing of common variants (SNV or indels) to determine embryo status. It also allows sex determination, analyzing SNPs in X and Y chromosomes, including variants in SRY gene.

Simultaneous screening of 8 frequently studied monogenic disorder genesEnables tracking of allele dropout eventsGenerate dense SNP haplotyesEasy to interpret softwareOptimized for PG-seq Rapid kit v2 workflow - REVPFZ (Additional S&H or Hazmat Fees May Apply)