Revvity HTRF Hman Phoho-Cyclin B1 (Ser126) Detection Kit, 500 Aay Point

Revvity This HTRF cell-based assay provides a convenient and accurate way to detect phosphorylated Cyclin B1 at Ser126. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity Cyclin B family members (including Cyclin B1 and Cyclin B2) are important regulators of cell cycle progression. They are integral mediators of the growth factor-dependent transition from G2 to Mitosis phases, playing the role of the regulatory subunit of CDK1. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity Cyclin B1 is upregulated in the presence of extracellular mitogenic stimuli and is subsequently rapidly downregulated by proteasomal degradation following its phosphorylation on Ser126. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity Cyclin B1 is often overexpressed in many cancers. Such abnormal overexpression of Cyclin B1 results in dysregulated CDK1 activity and can lead to tumorigenesis. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)