Revvity HTRF Human Phospho-cRAF (Ser43) Detection Kit, 500 Assay Points

cRaf is a proto-oncogene serine/threonine-protein kinase. The RAS-RAF-MEK signaling cascade plays a pivotal role in modulating cellular processes such as proliferation, differentiation, and survival. This pathway is often constitutively activated in human malignancies characterized by RAS or RAF oncogenic drivers. Developing chemotherapeutic cRaf inhibitors is an attractive area of research in oncology and infectious disease.