Revvity HTRF Human/Mouse Total CDK9 Detection Kit

The Total CDK9 cellular assay monitors CDK9 protein levels.

CDK9 in association with cyclins T or K, also called the positive transcription elongation factor (P-TEFb), is a general transcription factor that regulates transcription elongation through phosphorylation of the C-terminal tail domain (CTD) of RNA polymerase II (RNAP II). This crucial function and the evidence that transcriptional programs are dysregulated in cancer made make CDK9 an attractive target for anti-cancer therapies.