Revvity HTRF Human Total ADAR1 Detection Kit, 10,000 Assay Points

Revvity ADAR1 is one of two ADAR gene-coded enzymes. It binds to double-stranded RNA (dsRNA) and deaminates its adenosine into inosine (hypoxanthine). ADAR proteins act post-transcriptionally to alter RNA nucleotide contents. The deamination they operate interferes with the usual A:U pairing and destabilizes the RNA. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity The loss of regulation of ADAR1 & ADAR2 is involved in the development and progression of multiple cancers, such as glioblastomas, melanomas, or acute leukemias. On top of their role in oncogenesis, ADAR enzymes are suspected of contributing to the aggravation of some infectious diseases like HIV and measles, but also of mental disorders such as depression, epilepsy, and schizophrenia. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)