Revvity HTRF Human and Mouse Total RNA Pol II Detection Kit, 500 Assay Points

Revvity RNA polymerase II (RNA Pol II) is one of the primary enzymes responsible for expressing protein-encoding genes and some small nuclear RNAs. The carboxy-terminal domain (CTD) of RNA Pol II undergoes a cycle of phosphorylation, catalyzed mainly by members of the cyclin-dependent kinase (CDK) family. RNA Pol II CTD phosphorylation allows it to temporally couple transcription with transcription-associated processes (binding specificity of the CTD for particular factors is determined by the site-specific phosphorylation/dephosphorylation events). - REVPFZ (Additional S&H Or Hazmat Fees May Apply)