Revvity Ghrelin (Human), , 25µci

Revvity 25 µCi Quantities of Ghrelin (human), [His[¹²⁵I]] are available for your research. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (B_max), dissociation constants (K_d), association and dissociation rates (k_on and k_off), and inhibitor constants (K_i) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity References for NEX388: - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Gauna, C., van de Zande, B., van Kerkwijk, A., Themmen, A.P., van der Lely, A.J., Delhanty, P.J. (2007), Unacylated ghrelin is not a functional antagonist but a full agonist of the type 1a growth hormone secretagogue receptor (GHS-R). Mol Cell Endocrinol, 274 (1-2): 30-34.Leung, P.K., Chow, K.B., Lau, P.N., Chu, K.M., Chan, C.B., Cheng, C.H., Wise, H. (2007), The truncated ghrelin receptor polypeptide (GHS-R1b) acts as a dominant-negative mutant of the ghrelin receptor. Cell Signal, 19 (5): 1011-1022.