Revvity Sunitinib-Red, 1 Nmol

Revvity This compound is derived from Sunitinib, which is a well known inhibitor of the PDGF and VEGF RTK families. Sunitinib, which is an ATP-competitive Kinase inhibitor, is used as a drug to treat renal cell carcinoma and imatinib-resistant gastrointestinal stromal tumors. It has been shown to bind with an affinity of <100 nM to about 18% of the Kinases (both RTK and Ser/Thr). It is therefore useful to address multiple Kinases in the HTRF Kinase Binding assay platform.. The ‘d2’ fluorescent dye used absorbs with its maximum near 650 nm and fluoresces near 670 nm. It is used as an acceptor molecule in HTRF assays. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity Sunitinib-Red is supplied as a 25 µM solution in DMSO. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)