Revvity AlphaLISA SureFire Ultra Human Phospho-PI3K p85 (Tyr467) Detection Kit, 500 Assay Points

Revvity Phosphorylated Phosphoinositide 3-kinase regulatory subunit p85 (p-PI3 Kinase p85) is a regulatory subunit of the PI3K enzyme, which plays a critical role in cell growth, survival, and metabolism.  The p85 subunit binds to the p110 catalytic subunit, stabilizing it in an inhibited state under normal conditions. Upon activation by growth factors or hormones, p85 undergoes conformational changes that release the inhibition on p110, triggering downstream signaling pathways such as AKT. Aberrations in PI3K signaling are frequently observed in cancers, making it a prominent target for anti-cancer therapies. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity The AlphaLISA SureFire Ultra Human Phospho-PI3K p85 (Tyr467) Detection Kit is a sandwich immunoassay for the quantitative detection of phospho-PI3K p85 (Tyr467) in cellular lysates, using Alpha Technology. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity Formats: - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 μL reaction volume.The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μL reaction volume.The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μL reaction volume.The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μL reaction volume.

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Revvity AlphaLISA SureFire Ultra kits are compatible with: - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Cell and tissue lysatesAntibody modulatorsBiotherapeutic antibodies

Revvity   - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity Alpha SureFire Ultra kits can be used for: - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Cellular kinase assaysReceptor activation studiesScreening

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