Revvity AlphaLISA SureFire Ultra Human Phospho-JAK1 (Tyr1034/1035) Detection Kit, 500 Assay Points

Revvity Janus kinase 1 (JAK1) is a non-receptor tyrosine kinase essential for cytokine and growth factor signaling. JAK1 interacts with cytokine receptors and activates STAT transcription factors, which dimerize and translocate to the nucleus, regulating genes involved in immune function, cell survival, and proliferation. Aberrant activation of JAK1 is linked to leukemias, lymphomas, and autoimmune diseases such as rheumatoid arthritis and Crohns disease, where it contributes to inflammation. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity The AlphaLISA SureFire Ultra Human Phospho-JAK1 (Tyr1034/1035) Detection Kit is a sandwich immunoassay for the quantitative detection of phospho-JAK1 in cellular lysates, using Alpha Technology. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity Formats: - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 μL reaction volume.The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μL reaction volume.The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μL reaction volume.The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μL reaction volume.

Revvity AlphaLISA SureFire Ultra kits are compatible with: - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Cell and tissue lysatesAntibody modulatorsBiotherapeutic antibodies

Revvity AlphaLISA SureFire Ultra kits can be used for: - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Cellular kinase assaysReceptor activation studiesHigh-throughput screening for preclinical studies - REVPFZ (Additional S&H or Hazmat Fees May Apply)