Revvity AlphaLISA SureFire Ultra Human and Mouse Phospho-JAK2 (Tyr1008) Detection Kit, 500 Assay Points

Revvity Janus kinase 2 (JAK2) is a crucial component of the JAK-STAT signaling pathway, which governs cell growth, differentiation, and immune responses. JAK2 works in concert with cytokine receptors to activate STAT transcription factors, modulating gene expression. Mutations in JAK2 are associated with hematologic malignancies, including AML, as well as autoimmune diseases like Crohns disease and ulcerative colitis, which are characterized by severe inflammation. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity The AlphaLISA SureFire Ultra Human and Mouse Phospho-JAK2 (Tyr1008) Detection Kit is a sandwich immunoassay for the quantitative detection of phospho-JAK2 in cellular lysates, using Alpha Technology. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity Formats: - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 μL reaction volume.The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μL reaction volume.The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μL reaction volume.The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μL reaction volume.

Revvity AlphaLISA SureFire Ultra kits are compatible with: - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Cell and tissue lysatesAntibody modulatorsBiotherapeutic antibodies

Revvity AlphaLISA SureFire Ultra kits can be used for: - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Cellular kinase assaysReceptor activation studiesHigh-throughput screening for preclinical studies - REVPFZ (Additional S&H or Hazmat Fees May Apply)