Revvity AlphaLISA SureFire Ultra Human Total AXIN-2 Detection Kit, 500 Assay Points

Revvity AXIN-2 is a scaffold protein crucial for the WNT/β-catenin signaling pathway, promoting β-catenin degradation by assembling the destruction complex with APC, GSK3β, and CK1α. Dysregulation of AXIN-2 disrupts β-catenin levels, driving cancers such as colorectal cancer. Loss of AXIN-2 function is also observed in breast cancer and neuroblastoma. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity The AlphaLISA SureFire Ultra Human Total AXIN-2 Detection Kit is a sandwich immunoassay for the quantitative detection of total AXIN-2 in cellular lysates, using Alpha Technology. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity Formats: - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 μL reaction volume.The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μL reaction volume.The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μL reaction volume.The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μL reaction volume.

Revvity AlphaLISA SureFire Ultra kits are compatible with: - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Cell and tissue lysatesAntibody modulatorsBiotherapeutic antibodies

Revvity AlphaLISA SureFire Ultra kits can be used for: - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Cellular kinase assaysReceptor activation studiesHigh-throughput screening for preclinical studies - REVPFZ (Additional S&H or Hazmat Fees May Apply)