Revvity AlphaLISA SureFire Ultra Human and Mouse Total PAX8 Detection Kit, 100 Assay Points

PAX8 is a transcription factor essential for the development and function of the thyroid gland, kidneys, and reproductive system. It regulates thyroid-specific genes such as thyroglobulin and thyroid peroxidase in response to TSH signaling. Aberrant PAX8 expression is observed in cancers, including ovarian, endometrial, and renal cancers, where it is used as a diagnostic marker and contributes to tumor progression.

The AlphaLISA SureFire Ultra Human and Mouse Total PAX8 Detection Kit is a sandwich immunoassay for the quantitative detection of total PAX8 in cellular lysates, using Alpha Technology.

Formats:

The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 μL reaction volume.The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μL reaction volume.The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μL reaction volume.The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μL reaction volume.

AlphaLISA SureFire Ultra kits are compatible with:

Cell and tissue lysatesAntibody modulatorsBiotherapeutic antibodies

AlphaLISA SureFire Ultra kits can be used for:

Cellular kinase assaysReceptor activation studiesHigh-throughput screening for preclinical studies - REVPFZ (Additional S&H or Hazmat Fees May Apply)