Revvity Alphalisa Surefire Ultra Human Total Cdk7 Detect

Revvity Cyclin-dependent kinase 7 (CDK7), or cell division protein kinase 7, is encoded by the CDK7 gene which is a member of the CDK family. CDK7 has dual functions, as a CDK–activating kinase (CAK) that regulates cell cycle progression by phosphorylation of CDK1, CDK2, and CDK4/6, and as a component of transcription factor II H (TFIIH) that regulates transcriptional initiation through phosphorylation of RNA polymerase II C-terminal domain. Inhibition of CDK7 offers an opportunity for restoring controlled cell cycle through regulating multiple cell cycle checkpoints, making it a cancer therapy target. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity The AlphaLISA SureFire Human Total CDK7 Detection Kit is a sandwich immunoassay for the quantitative detection of total CDK7 in cellular lysates, using Alpha Technology. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Formats

The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 μL reaction volume.The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μL reaction volume.The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μL reaction volume.The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μL reaction volume.

AlphaLISA SureFire Ultra kits are compatible with

Cell and tissue lysatesAntibody modulatorsBiotherapeutic antibodies

Alpha SureFire kits can be used for

Cellular kinase assaysReceptor activation studiesScreening