Revvity AlhaLISA SreFire Ultra Hman Total c-FOS Detection Kit, 10,000 Aay Point

Revvity Protein c-Fos is encoded by the FOS gene, a proto-oncogene that is the human homolog of the retroviral oncogene v-fos. The Activator Protein-1 (AP-1) complex is formed when c-Fos and c-Jun form a heterodimer. This complex binds DNA at specific AP-1 sites in the promoter and enhancer regions of target genes, converting extracellular signals into changes in gene expression. Additionally, posttranslational alterations brought on by phosphorylation by various kinases, such as MAPK, CDC2, PKA, or PKC, regulate its activity. C-Fos plays an important role in numerous cellular functions, including cell proliferation, differentiation, survival, genes associated with hypoxia, and has been found to be overexpressed in a variety of cancers. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity   - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity The AlphaLISA SureFire Ultra Human Total c-FOS Detection Kit is a sandwich immunoassay for the quantitative detection of total c-FOS in cellular lysates, using Alpha Technology. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity  Formats: - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 μL reaction volume.The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μL reaction volume.The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μL reaction volume.The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μL reaction volume.

Revvity AlphaLISA SureFire Ultra kits are compatible with: - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Cell and tissue lysatesAntibody modulatorsBiotherapeutic antibodies

Revvity Alpha SureFire kits can be used for: - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Cellular kinase assaysReceptor activation studiesScreening