Revvity AlphaLISA SureFire Ultra Human Phospho-Tau (Thr205) Detection Kit, 10,000 Assay Points

Revvity Tau, also known as MAPT (Microtubule Associated Protein Tau), is a phosphoprotein that is mostly produced in neurons of the central nervous system and is involved in microtubule construction and stability. Around 85 phosphorylation sites are present in Tau, and numerous kinases, including CDK5, MAP kinase, and GSK3 (Taus primary kinase), can phosphorylate these sites. Numerous neurodegenerative diseases, including Tauopathy, Parkinsons, and Alzheimers, are characterized by Tau hyperphosphorylation and aggregation. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity The AlphaLISA SureFire Human Phospho-Tau (Thr205) Detection Kit is a sandwich immunoassay for the quantitative detection of phosphorylated tau Thr205 in cellular lysates, using Alpha Technology. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Formats

The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 μL reaction volume.The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μL reaction volume.The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μL reaction volume.The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μL reaction volume.

AlphaLISA SureFire Ultra kits are compatible with

Cell and tissue lysatesAntibody modulatorsBiotherapeutic antibodies

Alpha SureFire kits can be used for

Tau assayCellular kinase assaysReceptor activation studiesScreening