Revvity AlphaLISA SureFire Ultra Human Total PAX2 Detection Kit, 10,000 Assay Points

PAX2 is a transcription factor in the paired box (PAX) gene family that governs the development of organs like the kidneys, eyes, and central nervous system. It binds DNA via its paired domain to regulate embryonic gene expression. PAX2 mutations are linked to neurodevelopmental disorders, including autism and epilepsy, and its dysregulation contributes to cancers such as renal cell carcinoma and ovarian cancer, where it supports tumor survival and growth.

The AlphaLISA SureFire Ultra Human Total PAX2 Detection Kit is a sandwich immunoassay for the quantitative detection of total PAX2 in cellular lysates, using Alpha Technology.

Formats:

The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 μL reaction volume.The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μL reaction volume.The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μL reaction volume.The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μL reaction volume.

AlphaLISA SureFire Ultra kits are compatible with:

Cell and tissue lysatesAntibody modulatorsBiotherapeutic antibodies

AlphaLISA SureFire Ultra kits can be used for:

Cellular kinase assaysReceptor activation studiesHigh-throughput screening for preclinical studies - REVPFZ (Additional S&H or Hazmat Fees May Apply)