Sigma-Aldrich storage temp. 2-8°C Related Categories Biomedical Materials Drug Delivery Formulations

NanoFabTx^™ NanoFlash PEG-PLA drug formulation screening kit is a ready to use nanoformulation kit for flash nanoprecipitation synthesis of PEGylated PLA nanoparticles for drug delivery research applications. This kit contains rationally selected PEGylated PLA polymers and stabilizer, enabling users to screen and select nanoformulations without the need for lenghty trial and error optimization. These PEGylated PLA polymers have been widely used in drug delivery systems for controlled drug release of many different types of therapeutic molecules.

This kit has been curated and designed for flash nanoprecipitiaton (FNP) nanoparticle synthesis using a confined impingement jet (CIJ) mixer, such as the NanoFabTx^™ NanoFlash CIJ Mixer, and detailed step-by-step instructions are provided.

• Ready-to-use nanoformulation kit for PEGylated nanoparticles
• Step-by-step flash nanoprecipitation protocol
• Create specifically sized, biodegradable, PEGylated PLA nanoparticles
• Maximize the encapsulation of hydrophobic drugs
• Two different PEGylated PLAs are included
• Optimized for 60 nm-150 nm nanoparticles

A flash nanoprecipitation protocol to prepare drug-encapsulated nanoparticles using the NanoFabTx^™ NanoFlash CIJ Mixer is included and can be found under the Protocol section of this page.

NANOFABTX is a trademark of Sigma-Aldrich Co. LLC