Sigma-Aldrich Quality Level 100 assay ≥95% form powder or crystals color White to Beige storage temp

Name: Sigma-Aldrich Quality Level 100 assay ≥95% form powder or crystals color White to Beige storage temp
SKU: SIALUPENN-936510-50MG
Price: 315.00 USD

List Price $315.00 Your Price $315.00

Sigma-Aldrich Quality Level 100 assay ≥95% form powder or crystals color White to Beige storage temp. 2-8°C SMILES string - SIALUPENN (Additional S&H or Hazmat Fees may Apply)

NETA PART: SIALUPENN-936510-50MG

MFG.PART: 936510-50MG

UNSPSC: 41122409

Manufacturer: Sigma-Aldrich

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Description

Quality Level

100

assay

≥95%

form

powder or crystals

color

White to Beige

storage temp.

2-8°C

SMILES string

C([C@@H](NC(COCCOCC(O)=O)=O)[C@](C)(C)C)(=O)N1[C@H](C(NCC2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@@H](O)C1

InChI key

SVWILERVXWUPQA-TYBLODHISA-N

Application

This is a functionalized von Hippel-Lindau (VHL) ligand. It contains a terminal carboxyl group for conjugation with amine linkers. A basic building block for development of a protein degrader library.

Technology Spotlight:

Degrader Building Blocks for Targeted Protein Degradation
Protein Degrader Building Blocks

Other Notes

Targeted Protein Degradation by Small Molecules
Destruction of DNA-Binding Proteins by Programmable Oligonucleotide PROTAC (O′PROTAC): Effective Targeting of LEF1 and ERG
Small-Molecule PROTACS: New Approaches to Protein Degradation
Targeted Protein Degradation: from Chemical Biology to Drug Discovery
Impact of linker length on the activity of PROTACs

Legal Information

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c