Sigma-Aldrich Product Name DMS 92, 95062825 biological source human lung (bone marrow metastasis)

Human Caucasian lung small cell carcinoma, metastasis to bone marrow

DMS 92 was obtained from a bone marrow aspirate of an untreated 39 year old male at time of diagnosis. The isolated cells were identified as small cell carcinoma of the lung (SCLC). DMS 92 cells secrete adrenocorticotropin (ACTH), bombesin (BN), oxytocin-neurophysin (OT-NP) and 17 β-estradiol. Cells produce tumours in athymic nude mice.

Human lung tumour model

Waymouth′s MB 752/1 + 2mM Glutamine + 10% Foetal Bovine Serum (FBS) (Heat Inactivated).

Maintain cultures between 3-9x100,000 cells/ml; 5% CO₂; 37°C.

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