Revvity AlphaLISA SureFire Ultra Human Phospho-Ret (Tyr905) Detection Kit, 50,000 assay points

Revvity Rearranged during transfection (Ret) is a receptor tyrosine kinase that governs cell growth, survival, and differentiation. Upon activation by glial cell line-derived neurotrophic factor (GDNF) family ligands, Ret triggers downstream signaling cascades, including MAPK, PI3K/AKT, and JAK/STAT. Ret fusions and activating mutations drive oncogenesis in thyroid cancer, lung adenocarcinoma, and multiple endocrine neoplasia (MEN) syndromes, making it a key target for precision therapies. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity The AlphaLISA SureFire Ultra Human Phospho-Ret (Tyr905) Detection Kit is a sandwich immunoassay for the quantitative detection of phospho-Ret (Tyr905) in cellular lysates, using Alpha Technology. - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

Revvity Formats: - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

• The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 μL reaction volume.
• The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μL reaction volume.
• The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μL reaction volume.
• The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μL reaction volume.

Revvity AlphaLISA SureFire Ultra kits are compatible with: - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

• Cell and tissue lysates
• Antibody modulators
• Biotherapeutic antibodies

Revvity AlphaLISA SureFire Ultra kits can be used for: - REVPFZ (Additional S&H Or Hazmat Fees May Apply)

• Cellular kinase assays
• Receptor activation studies
• High-throughput screening for preclinical studies