Sigma-Aldrich FLUORESCEIN ISOTHIOCYANATE-DEXTRAN AV.

Dextran labeled with fluorescein isothiocyanate for possible use in perfusion studies in animals.

FITC-dextran is used extensively in microcirculation and cell permeability research utilizing microfluorimetry. FITC-dextran has been used to study plant cell wall porosity and capillary permeability. Plasma proteins have been shown not to bind to FITC-dextran.

FITC-dextran is used in cardiovascular, microcirculation, perfusion, cell monolayer and cell membrane permeability research as fluorescent flux tracer compound that supports the measurement of processes such as blood flow, membrane damage, vascular drainage and renal elimination.[1] Small FITC-dextrans are also used to measure processes such as endocytosis. FITC-Dextran 250 (FD 250) may be used as a model compound for development of methods to deliver molecules into protoplasts and to study drug release from structures such as hydrogels and liposomes. It may be used as a model compound to study microvasculature and blood brain barrier.[2]

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.