Sigma-Aldrich V-9302. ≥98% (HPLC). 5 mg

Name: Sigma-Aldrich V-9302. ≥98% (HPLC). 5 mg
SKU: SIAL-SML3525-5MG
Price: 82.82 USD

List Price $82.82 Your Price $82.82

Sigma-Aldrich V-9302. ≥98% (HPLC). 5 mg - SIAL (Additional S&H Or Hazmat Fees May Apply)

NETA PART: SIAL-SML3525-5MG

MFG.PART: SML3525-5MG

UNSPSC: 41122409

Manufacturer: Sigma-Aldrich

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Description

Quality Level

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

-10 to -25°C

SMILES string

CC1=CC=CC(COC2=C(C=CC=C2)CN(CC3=CC=CC=C3OCC4=CC=CC(C)=C4)CC[C@@H](C(O)=O)N)=C1

InChI

1S/C34H38N2O4/c1-25-9-7-11-27(19-25)23-39-32-15-5-3-13-29(32)21-36(18-17-31(35)34(37)38)22-30-14-4-6-16-33(30)40-24-28-12-8-10-26(2)20-28/h3-16,19-20,31H,17-18,21-24,35H2,1-2H3,(H,37,38)/t31-/m0/s1

InChI key

YGKNVAAMULVFNN-HKBQPEDESA-N

Biochem/physiol Actions

Competitive antagonist of the amino acid transporter ASCT2 (SLC1A5) with anti-tumor activity

V-9302 is a selective competitive antagonist of the amino acid transporter ASCT2 (SLC1A5) with anti-tumor activity. V-9302 caused reduced cellular viability and increased cell death in a panel of cancer cell lines and reduced tumor cell growth in both HCT-116 and HT29 (Fig. 5f) xenograft models.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c