Sigma-Aldrich 5,5-Diphenylhydantoin. ≥98%. 5 g

Name: Sigma-Aldrich 5,5-Diphenylhydantoin. ≥98%. 5 g
SKU: SIAL-D4007-5G
Price: 58.23 USD

List Price $58.23 Your Price $58.23

Sigma-Aldrich 5,5-Diphenylhydantoin. ≥98%. 5 g - SIAL (Additional S&H Or Hazmat Fees May Apply)

NETA PART: SIAL-D4007-5G

MFG.PART: D4007-5G

UNSPSC: 51000000

Manufacturer: Sigma-Aldrich

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Description

assay

≥98%

form

powder

mp

293-295 °C (lit.)

solubility

DMSO: soluble

SMILES string

O=C1NC(=O)C(N1)(c2ccccc2)c3ccccc3

InChI

1S/C15H12N2O2/C18-13-15(17-14(19)16-13,11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H,(H2,16,17,18,19)

InChI key

CXOFVDLJLONNDW-UHFFFAOYSA-N

Gene Information

human ... CNR1(1268), CNR2(1269), CYP2C9(1559), SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)
rat ... Faah(29347), Scn1a(81574), Scnn1g(24768), Slc6a1(79212)

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Related Categories

Bioactive Small Molecule Inhibitors

General description

5,5-Diphenylhydantoin is an anticonvulsant, which is used to treat tonic-clonic seizures, complex partial seizures and neurosurgical related seizures. It induces osteoblast proliferation and differentiation.[1] 5,5-Diphenylhydantoin used to treat epilepsy.[2] It reduces the hyperexcitability of tissues and may be associated with cerebellar atrophy.[1]

Application

5,5-Diphenylhydantoin has been used for phenytoin treatment.[3] It has also been used to slow down or prevent mesoendoderm cell migration.[4]

Biochem/physiol Actions

Anticonvulsant.

Reduces incidence of grand mal seizures; appears to stabilize excitable membranes perhaps through effects on Na⁺, K⁺, and Ca²⁺ channels.

pictograms

GHS08,GHS07

signalword

Danger

hcodes

H302,H351,H360FD

pcodes

P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c