Sigma-Aldrich Oxaloacetic acid. ≥97% (HPLC). 1 g

Name: Sigma-Aldrich Oxaloacetic acid. ≥97% (HPLC). 1 g
SKU: SIAL-O4126-1G
Price: 81.43 USD

List Price $81.43 Your Price $81.43

Sigma-Aldrich Oxaloacetic acid. ≥97% (HPLC). 1 g - SIAL (Additional S&H Or Hazmat Fees May Apply)

NETA PART: SIAL-O4126-1G

MFG.PART: O4126-1G

UNSPSC: 12352107

Manufacturer: Sigma-Aldrich

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Description

Quality Level

200

assay

≥97% (HPLC)

form

powder

solubility

H₂O: 100 mg/mL, clear to slightly hazy, colorless to light yellow

storage temp.

−20°C

SMILES string

OC(=O)CC(=O)C(O)=O

InChI

1S/C4H4O5/c5-2(4(8)9)1-3(6)7/h1H2,(H,6,7)(H,8,9)

InChI key

KHPXUQMNIQBQEV-UHFFFAOYSA-N

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General description

Oxaloacetic acid is a dicarboxylic acid. It is an intermediate in the citric acid cycle. It is highly soluble in water and is present ubiquitously. It is produced in the mitochondria by the action of pyruvate carboxylase on pyruvate. Breakdown products of oxaloacetate includes malate, pyruvate and aspartic acid.[1]

Application

Oxaloacetic acid has been used as a substrate for measuring citrate synthase activity in cybrids[2] and neuroblastoma cells.[3] It has also been used for measuring malate dehydrogenase reactivation.[4]

Biochem/physiol Actions

Oxaloacetic acid being an intermediate in the tri carboxylic cycle is central to metabolism. It is part of gluconeogenesis pathway. Mutation in pyruvate carboxylase leads to decreased production of oxaloacetate.[1] It inhibits succinate dehydrogenase and is a key regulator of mitochondrial metabolism.[5]

Pictograms

GHS07

signalword

Warning

hcodes

H319

pcodes

P264 - P280 - P305 + P351 + P338 - P337 + P313

Hazard Classifications

Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c