Sigma-Aldrich Phenylmethanesulfonyl fluoride. ≥99.0% (T). 1 g

Name: Sigma-Aldrich Phenylmethanesulfonyl fluoride. ≥99.0% (T). 1 g
SKU: SIAL-78830-1G
Price: 89.21 USD

List Price $89.21 Your Price $89.21

Sigma-Aldrich Phenylmethanesulfonyl fluoride. ≥99.0% (T). 1 g - SIAL (Additional S&H Or Hazmat Fees May Apply)

NETA PART: SIAL-78830-1G

MFG.PART: 78830-1G

UNSPSC: 12352200

Manufacturer: Sigma-Aldrich

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Description

biological source

synthetic

assay

≥99.0% (T)

form

powder or crystals

impurities

≤0.2% water

mp

92-95 °C

solubility

anhydrous isopropanol: soluble 35 mg/mL, clear to faintly hazy, colorless to faintly yellow (Heating required)

storage temp.

room temp

SMILES string

FS(=O)(=O)Cc1ccccc1

InChI

1S/C7H7FO2S/C8-11(9,10)6-7-4-2-1-3-5-7/h1-5H,6H2

InChI key

YBYRMVIVWMBXKQ-UHFFFAOYSA-N

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Application

Phenylmethanesulfonyl fluoride has been used as a component in radioimmunoprecipitation buffer for western blot analysis.[1][2] It has also been used as a component in the RAW264.7 cell lysis buffer for western blotting.[3]

Biochem/physiol Actions

Phenylmethanesulfonyl fluoride has the ability to enhance the stability of plasma lipidome in lipidomic and metabolomic analysis.[4] This serine protease inhibitor reduces the naloxone-precipitated withdrawal jumping behavior in morphine-dependent mice.[5]

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Specific trypsin and chymotrypsin inhibitor.[6] Less toxic substitute for diisopropylfluorophosphate. Potentiates the effects of ischemia on brain mitochondria through its inhibition of phospholipase C.[7]

Specific trypsin and chymotrypsin inhibitor[6]; Less toxic substitute for diisopropylfluorophosphate. Potentiates the effects of ischemia on brain mitochondria through its inhibition of phospholipase C.[7]

pictograms

GHS06,GHS05

signalword

Danger

hcodes

H301,H314

pcodes

P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363

Hazard Classifications

Acute Tox. 3 Oral - Skin Corr. 1B

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c