We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn about our cookie policy.
Sigma-Aldrich β-Estradiol 17-(β-D-glucuronide) sodium salt. ≥98% (HPLC), Estradiol metabolite, powder. 25 mg
List Price $425.72 Your Price $425.72
Sigma-Aldrich β-Estradiol 17-(β-D-glucuronide) sodium salt. ≥98% (HPLC), Estradiol metabolite, powder. 25 mg - SIAL (Additional S&H Or Hazmat Fees May Apply)
NETA PART: SIAL-E1127-25MG
MFG.PART: E1127-25MG
UNSPSC: 51180000
Manufacturer: Sigma-Aldrich
Product Name
β-Estradiol 17-(β-D-glucuronide) sodium salt,
sterility
non-sterile
assay
≥98% (HPLC)
form
powder
solubility
0.1 M NaOH: 10 mg/mL, clear to slightly hazy, colorless to faintly yellow
shipped in
ambient
storage temp.
−20°C
SMILES string
[Na].CC12CCC3C(CCc4cc(O)ccc34)C1CCC2OC5OC(C(O)C(O)C5O)C(O)=O
InChI
1S/C24H32O8.Na.H/c1-24-9-8-14-13-5-3-12(25)10-11(13)2-4-15(14)16(24)6-7-17(24)31-23-20(28)18(26)19(27)21(32-23)22(29)30;;/h3,5,10,14-21,23,25-28H,2,4,6-9H2,1H3,(H,29,30);;
InChI key
GPLPNZUTAJWRLU-UHFFFAOYSA-N
Related Categories
Bioactive Small Molecules
Application
β-Estradiol 17-(β-D-glucuronide) sodium salt has been used as a standard to determine the quantity of β-Estradiol 17-(β-D-glucuronide) during UDP-glucuronosyltransferase assay.[1] It has also been used as a constituent of modified synthetic oviduct fluid (M-SOF) for maturation of bovine cumulus oocyte complexes (COC).[2][3]
Biochem/physiol Actions
Estradiol 17-(β-D-glucuronide) (E217G) is a naturally occurring conjugated estrogen. It is formed in the liver and later excreted in bile. Increased concentrations of E217G leads to the development of cholestasis during the later stages of pregnancy, a condition which occurs with high frequency in the Dubin-Johnson syndrome.[4]
Features and Benefits
This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
pictograms
GHS08,GHS07
signalword
Warning
hcodes
H302 + H312 + H332,H351
pcodes
P202 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P308 + P313
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
PPE
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
| SKU | SIAL-E1127-25MG |
|---|---|
| Supplier Part Number | E1127-25MG |
| UM | EA |
| UNSPSC | 51180000 |
| Manufacturer | Sigma-Aldrich |
| Temperature | -20C |
| Refrigerated-Frozen | Y |
| ProductLine | SIAL |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 10.000000 |
| Lead Time | 9 |
| CAS Number | 15087-02-2 |
| Energy Star | No |
| Green | No |
| Controlled | N |