Sigma-Aldrich Honokiol. ≥98% (HPLC), Antiangeogenic reagent, powder. 10 mg

Name: Sigma-Aldrich Honokiol. ≥98% (HPLC), Antiangeogenic reagent, powder. 10 mg
SKU: SIAL-H4914-10MG
Price: 225.04 USD

List Price $225.04 Your Price $225.04

Sigma-Aldrich Honokiol. ≥98% (HPLC), Antiangeogenic reagent, powder. 10 mg - SIAL (Additional S&H Or Hazmat Fees May Apply)

NETA PART: SIAL-H4914-10MG

MFG.PART: H4914-10MG

UNSPSC: 12352100

Manufacturer: Sigma-Aldrich

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Description

Product Name

Honokiol, ≥98% (HPLC), powder

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

solubility

DMSO: 36 mg/mL

antibiotic activity spectrum

Gram-positive bacteria
neoplastics

mode of action

DNA synthesis | interferes

storage temp.

2-8°C

SMILES string

Oc1ccc(cc1CC=C)-c2cc(CC=C)ccc2O

InChI

1S/C18H18O2/c1-3-5-13-7-9-18(20)16(11-13)14-8-10-17(19)15(12-14)6-4-2/h3-4,7-12,19-20H,1-2,5-6H2

Looking for similar products? Visit Product Comparison Guide

General description

Honokiol exhibits analgesic, antithrombotic, antispasmodic, antidepressant, antimicrobial and neuroprotective effects.[1] It regulates gamma-aminobutyric acid (GABA) A receptors.[2] Honokiol is associated with an increased risk of bleeding.[3] It prevents platelet aggregation, protects myocardium from ischemic damage and inhibits ventricular arrhythmia.[4]

Application

Honokiol has been used:

to study its effects on plasmid hSirt3^102-399 deacetylation activity[5]
as an antioxidant to study its cytoprotective role in human ovarian cancer cells (SKOV-3) and Chinese hamster ovary cells (CHOK1)[6]
to explore its effects on oxidative stress and mitochondrial dysfunction via a sirt3-dependent manner[7]
for intracerebroventricular (ICV) cannulation[8][9]

Biochem/physiol Actions

Honokiol is a natural biphenyl neolignan from magnolia extract. It is antiangiogenic, antitumor, and anxiolytic.

Features and Benefits

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

pictograms

GHS05,GHS09

signalword

Danger

hcodes

H318,H411

pcodes

P273 - P280 - P305 + P351 + P338 - P391 - P501

Hazard Classifications

Aquatic Chronic 2 - Eye Dam. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c