Sigma-Aldrich Zearalanone. ≥98% (TLC), mycotoxin, powder. 5 mg

Name: Sigma-Aldrich Zearalanone. ≥98% (TLC), mycotoxin, powder. 5 mg
SKU: SIAL-Z0167-5MG
Price: 269.12 USD

List Price $269.12 Your Price $269.12

Sigma-Aldrich Zearalanone. ≥98% (TLC), mycotoxin, powder. 5 mg - SIAL (Additional S&H Or Hazmat Fees May Apply)

NETA PART: SIAL-Z0167-5MG

MFG.PART: Z0167-5MG

UNSPSC: 12352200

Manufacturer: Sigma-Aldrich

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Description

Product Name

Zearalanone,

sterility

non-sterile

Quality Level

200

assay

≥98% (TLC)

form

powder

solubility

methanol: 9.80-10.20 mg/mL, clear, colorless

shipped in

ambient

storage temp.

−20°C

SMILES string

C[C@H]1CCCC(=O)CCCCCc2cc(O)cc(O)c2C(=O)O1

InChI

1S/C18H24O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h10-12,20-21H,2-9H2,1H3/t12-/m0/s1

General description

Zearalanone (ZEA) or F-2 toxin,[1] a nonsteroidal estrogenic mycotoxin is produced by various Fusarium species.[2] Fusarium graminearum is considered as the primary producer of zearalanone.[3] It is usually seen in moldy hay, high-moisture corn, corn infected before harvest etc.[1]

Application

Zearalanone has been used:

as mycotoxin to study its effects on the histology of ovaries in pre-pubertal bitches[4]
as a mycotoxin to investigate its influence on selected immunological, haematological and biochemical indexes in bitches[5]
as a standard to develop calibration curves in order to study its effects on progesterone and 17β-estradiol concentrations in peripheral blood and body weights of pre-pubertal female Beagle dogs[6]
as a standard to develop calibration curves to study its level of intoxication in women with neoplastic lesions in the reproductive tract[7]

Biochem/physiol Actions

Zearalanone is believed to cause vulvovaginitis and estrogenic responses in swine.[1]

pictograms

GHS08,GHS07

signalword

Warning

hcodes

H302 + H312 + H332,H315,H319,H335,H351

pcodes

P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P308 + P313

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c