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Sigma-Aldrich Isocitric Dehydrogenase (NADP) from porcine heart. 500 mg
List Price $279.56 Your Price $279.56
Sigma-Aldrich Isocitric Dehydrogenase (NADP) from porcine heart. Type I, 0.5-3.0 unit/mg solid (plus numerous enzyme activities associated with porcine heart). 500 mg - SIAL (Additional S&H Or Hazmat Fees May Apply)
NETA PART: SIAL-I1877-500MG
MFG.PART: I1877-500MG
UNSPSC: 12352204
Manufacturer: Sigma-Aldrich
biological source
Porcine heart
type
Type I
form
solid
specific activity
0.5-3.0 unit/mg solid (plus numerous enzyme activities associated with porcine heart)
storage temp.
−20°C
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Biochem/physiol Actions
Isocitrate dehydrogenase (IDH) plays a major role in the Krebs cycle by catalyzing the oxidative decarboxylation of isocitrate.[1] The oxidative decarboxylation of isocitrate generates α-ketoglutarate and NADPH. NADPH produced is essential for the production of fatty acids and cholesterol.[2] This NADP-dependent molecules serves as homodimers.[3]
Analysis Note
Crude
Other Notes
One unit will convert 1.0 μmole of isocitrate to α-ketoglutarate per min at pH 7.4 at 37°C.
pictograms
GHS08
signalword
Danger
hcodes
H334
pcodes
P261 - P284 - P501
Hazard Classifications
Resp. Sens. 1
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
PPE
Eyeshields, Gloves, type N95 (US)
| SKU | SIAL-I1877-500MG |
|---|---|
| Supplier Part Number | I1877-500MG |
| UM | EA |
| UNSPSC | 12352204 |
| Manufacturer | Sigma-Aldrich |
| ProductLine | SIAL |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 9 |
| Energy Star | No |
| Green | No |
| Controlled | N |