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Sigma-Aldrich N-Succinyl-Ala-Ala-Pro-Phe p-nitroanilide. Subtilisin substrate. 25 mg
List Price $133.75 Your Price $133.75
Sigma-Aldrich N-Succinyl-Ala-Ala-Pro-Phe p-nitroanilide. Subtilisin substrate. 25 mg - SIAL (Additional S&H Or Hazmat Fees May Apply)
NETA PART: SIAL-S7388-25MG
MFG.PART: S7388-25MG
UNSPSC: 41116127
Manufacturer: Sigma-Aldrich


Product Name
N-Succinyl-Ala-Ala-Pro-Phe p-nitroanilide,
storage temp.
−20°C
SMILES string
[H][C@]1(CCCN1C(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)CCC(O)=O)C(=O)N[C@@H](Cc2ccccc2)C(=O)Nc3ccc(cc3)[N+]([O-])=O
InChI
1S/C30H36N6O9/c1-18(31-25(37)14-15-26(38)39)27(40)32-19(2)30(43)35-16-6-9-24(35)29(42)34-23(17-20-7-4-3-5-8-20)28(41)33-21-10-12-22(13-11-21)36(44)45/h3-5,7-8,10-13,18-19,23-24H,6,9,14-17H2,1-2H3,(H,31,37)(H,32,40)(H,33,41)(H,34,42)(H,38,39)/t18-,19-,23-,24-/m0/s1
InChI key
LKDMKWNDBAVNQZ-WJNSRDFLSA-N
Gene Information
human ... FKBP10(60681)
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Related Categories
Bioactive Small Molecules
Amino Acid Sequence
N-Suc-Ala-Ala-Pro-Phe-pNA
General description
N-Succinyl-Ala-Ala-Pro-Phe p-nitroanilide is a colorimetric substrate for chymotrypsin, human leukocyte cathepsin g and peptidyl prolyl isomerase.
Application
N-Succinyl-Ala-Ala-Pro-Phe p-nitroanilide has been used as a substrate to determine chymotrypsin activity.[1][2]
N-Succinyl-Ala-Ala-Pro-Phe p-nitroanilide has been used:
- as a substrate for cathepsin g assay in bone marrow lysates.[3]
- in proteolytic activity assay of serine protease subtilisin carlsberg (SC).[4]
- as a substrate for neutrophil elastase, trypsin and chymotrypsin in protease assay.[5]
Biochem/physiol Actions
N-succinyl-Ala-Ala-Pro-Phe p-nitroanilide is a substrate for subtilisin[6] and proteases.[7]
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
PPE
Eyeshields, Gloves, type N95 (US)
| SKU | SIAL-S7388-25MG |
|---|---|
| Supplier Part Number | S7388-25MG |
| UM | EA |
| UNSPSC | 41116127 |
| Manufacturer | Sigma-Aldrich |
| Temperature | -20C |
| Refrigerated-Frozen | Y |
| ProductLine | SIAL |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 10.000000 |
| Lead Time | 9 |
| CAS Number | 70967-97-4 |
| Energy Star | No |
| Green | No |
| Controlled | N |

