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Sigma-Aldrich Methazolamide. ≥98% (HPLC), carbonic anhydrase inhibitor, powder. 50 mg
List Price $164.28 Your Price $164.28
Sigma-Aldrich Methazolamide. ≥98% (HPLC), carbonic anhydrase inhibitor, powder. 50 mg - SIAL (Additional S&H Or Hazmat Fees May Apply)
NETA PART: SIAL-SML0720-50MG
MFG.PART: SML0720-50MG
UNSPSC: 41116107
Manufacturer: Sigma-Aldrich
Product Name
Methazolamide, ≥98% (HPLC)
assay
≥98% (HPLC)
form
powder
storage condition
protect from light
color
white to beige
mp
208 °C (dec.) (lit.)
solubility
DMSO: 20 mg/mL, clear
storage temp.
2-8°C
SMILES string
CN1N=C(S\C1=N\C(C)=O)S(N)(=O)=O
InChI
1S/C5H8N4O3S2/c1-3(10)7-4-9(2)8-5(13-4)14(6,11)12/h1-2H3,(H2,6,11,12)/b7-4+
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Related Categories
Bioactive Small Molecule Inhibitors
Bioactive Small Molecules
Biochem/physiol Actions
Cell-permeable and potent carbonic anhydrase (CA) inhibitor
Methazolamide has a plasma half-life of 14 hours in humans. Methazolamide has relatively good lipid solubility and low plasma protein binding ability. Thus, it diffuses into tissues and fluids much more readily than acetazolamide, another carbonic anhydrase inhibitor. Methazolamide has less side effects than acetazolamide.[1]
Methazolamide is a cell-permeable and potent carbonic anhydrase (CA) inhibitor that is used in the treatment of glaucoma. Methazolamide is an insulin sensitizer that reduces hepatic glucose generation in animal models.
Other Notes
Light sensitive
Pictograms
GHS08,GHS07
signalword
Warning
hcodes
H302 + H312 + H332,H351
pcodes
P202 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P308 + P313
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
| SKU | SIAL-SML0720-50MG |
|---|---|
| Supplier Part Number | SML0720-50MG |
| UM | EA |
| UNSPSC | 41116107 |
| Manufacturer | Sigma-Aldrich |
| ProductLine | SIAL |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 9 |
| Energy Star | No |
| Green | No |
| Controlled | N |