Sigma-Aldrich WR99210 hydrochloride. ≥98% (HPLC). 5 mg

Name: Sigma-Aldrich WR99210 hydrochloride. ≥98% (HPLC). 5 mg
SKU: SIAL-SML2976-5MG
Price: 218.08 USD

List Price $218.08 Your Price $218.08

Sigma-Aldrich WR99210 hydrochloride. ≥98% (HPLC). 5 mg - SIAL (Additional S&H Or Hazmat Fees May Apply)

NETA PART: SIAL-SML2976-5MG

MFG.PART: SML2976-5MG

UNSPSC: 41116107

Manufacturer: Sigma-Aldrich

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Description

Quality Level

100

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

SMILES string

[Cl-].Clc1c(cc(c(c1)Cl)OCCCON2C(N=C(N=C2N)N)(C)C)Cl.[H+]

InChI

1S/C14H18Cl3N5O2.ClH/c1-14(2)21-12(18)20-13(19)22(14)24-5-3-4-23-11-7-9(16)8(15)6-10(11)17;/h6-7H,3-5H2,1-2H3,(H4,18,19,20,21);1H

InChI key

VOTSDCGUYAGUNS-UHFFFAOYSA-N

Biochem/physiol Actions

Potent P. falciparum dihydrofolate reductase (pfDHFR) inhibitor.

WR99210 is a potent inhibitor of Plasmodium falciparum dihydrofolate reductase (pfDHFR), which is a major malarial drug target. It has subnanomolar potency for the wild type, double mutant and quadruple mutant dihydrofolate reductases.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c