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Sigma-Aldrich Metformin. ≥97% (titration), solid, AMPK signaling activator, Calbiochem®. 5 g
List Price $197.20 Your Price $197.20
Sigma-Aldrich Metformin. ≥97% (titration), solid, AMPK signaling activator, Calbiochem®. 5 g - SIAL (Additional S&H Or Hazmat Fees May Apply)
NETA PART: SIAL-317240-5GM
MFG.PART: 317240-5GM
UNSPSC: 41116107
Manufacturer: Sigma-Aldrich
Product Name
Metformin, An antihyperglycemic agent that lowers blood glucose levels without stimulating insulin secretion, promoting weight gain or causing hypoglycemia.
Quality Level
100
description
Merck USA index - 14, 5938
assay
≥97% (titration)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
desiccated (hygroscopic)
color
white
solubility
water: 50 mg/mL
shipped in
ambient
General description
An anti-hyperglycemic agent that acts by lowering the hepatic output of glucose. Does not stimulate insulin secretion, promote weight gain, or cause hypoglycemia. Reported to stimulate AMP-activated protein kinase (AMPK), leading to the reduction in acetyl-CoA carboxylase (ACC) activity and induction of fatty acid oxidation.
An antihyperglycemic agent that lowers blood glucose levels without stimulating insulin secretion, promoting weight gain or causing hypoglycemia. Reported to stimulate AMP-activated protein kinase (AMPK) leading to the reduction in acetyl-CoA carboxylase (ACC) activity and induction of fatty acid oxidation.
Biochem/physiol Actions
Cell permeable: no
Primary Target
AMP-activated protein kinase (AMPK)
AMP-activated protein kinase (AMPK)
Product does not compete with ATP.
Reversible: no
Packaging
Packaged under inert gas
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Other Notes
Cleasby, M.E., et Al. 2004. Diabetes53, 3258.
Klein, J., et Al. 2004. J. Endocrinol.183, 299.
Zhou, g., et Al. 2001. J. Clin. Invest.108, 1167.
Lin, H.Z., et Al. 2000. Nat. Med.6, 998.
Klein, J., et Al. 2004. J. Endocrinol.183, 299.
Zhou, g., et Al. 2001. J. Clin. Invest.108, 1167.
Lin, H.Z., et Al. 2000. Nat. Med.6, 998.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Irritant (B)
pictograms
GHS07
signalword
Warning
hcodes
H302,H319
pcodes
P264 - P280 - P301 + P312 - P305 + P351 + P338 - P337 + P313 - P501
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2
Storage Class
11 - Combustible Solids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
| SKU | SIAL-317240-5GM |
|---|---|
| Supplier Part Number | 317240-5GM |
| UM | EA |
| UNSPSC | 41116107 |
| Manufacturer | Sigma-Aldrich |
| ProductLine | SIAL |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 10.000000 |
| Lead Time | 9 |
| Energy Star | No |
| Green | No |
| Controlled | N |