Sigma-Aldrich SQ 22536. ≥98% (HPLC), adenylate cyclase inhibitor, solid. 5 mg

Name: Sigma-Aldrich SQ 22536. ≥98% (HPLC), adenylate cyclase inhibitor, solid. 5 mg
SKU: SIAL-568500-5MG
Price: 251.72 USD

List Price $251.72 Your Price $251.72

Sigma-Aldrich SQ 22536. ≥98% (HPLC), adenylate cyclase inhibitor, solid. 5 mg - SIAL (Additional S&H Or Hazmat Fees May Apply)

NETA PART: SIAL-568500-5MG

MFG.PART: 568500-5MG

UNSPSC: 12352200

Manufacturer: Sigma-Aldrich

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Description

Product Name

SQ 22536, Cell-permeable adenylate cyclase inhibitor.

Quality Level

100

assay

≥98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze

color

off-white

solubility

DMSO: 25 mg/mL
water: 5 mg/mL

shipped in

ambient

storage temp.

2-8°C

General description

Cell-permeable adenylate cyclase inhibitor. Blocks PTH-stimulation of adenylate cyclase (IC₅₀ = 200 µM). Reduces PGE₂-induced inhibition of O₂^·– production.

Biochem/physiol Actions

Cell permeable: yes

Primary Target
adenylate cyclase

Product does not compete with ATP.

Reversible: no

Target IC₅₀: 200 µM against adenylate cyclase

Preparation Note

Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 2 weeks at 4°C.

Other Notes

Talpain, E., et Al. 1995. Br. J. Pharmacol. 114, 1459.
Tamaoki, J., et Al. 1993. Prostaglandins45, 363.
Fabbri, E., et Al. 1991. J. Enzyme Inhib.5, 87.
Goldsmith, B.A. and Abrams, T.W. 1991. Proc. Natl. Acad. Sci. USA 88, 9021.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Irritant (B)

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c