Sigma-Aldrich Orlistat. ≥98% (HPLC), solid, lipase inhibitor. 25 mg

Name: Sigma-Aldrich Orlistat. ≥98% (HPLC), solid, lipase inhibitor. 25 mg
SKU: SIAL-O4139-25MG
Price: 207.64 USD

List Price $207.64 Your Price $207.64

Sigma-Aldrich Orlistat. ≥98% (HPLC), solid, lipase inhibitor. 25 mg - SIAL (Additional S&H Or Hazmat Fees May Apply)

NETA PART: SIAL-O4139-25MG

MFG.PART: O4139-25MG

UNSPSC: 12352200

Manufacturer: Sigma-Aldrich

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Description

Product Name

Orlistat, ≥98%, solid

biological source

synthetic (organic)

assay

≥98%

form

solid

color

white

mp

<50 °C

solubility

DMSO: 19 mg/mL

originator

Roche

storage temp.

2-8°C

SMILES string

CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)[C@H](CC(C)C)NC=O

Looking for similar products? Visit Product Comparison Guide

General description

Orlistat acts as a gastric lipase inhibitor that reduces fat absorption.[1]

Application

Orlistat has been used as an inhibitor:

of fatty acid synthase in long-term estrogen-deprived (LTED) variant cell lines[2]
of lipase in screening lipase inhibition by raspberry extract[3]
in in vitro pancreatic lipase activity assay[4]

Biochem/physiol Actions

Orlistat impairs intestinal fat absorption and is effective in weight management. It is regarded as a safe drug for treating obesity.[5] It delays the progression of type 2 diabetes mellitus especially in obese and improves glycemic parameters.[6] Long term usage of orlistat results in improved weight reduction and it may not contribute in colorectal carcinogenesis.[7]

Orlistat, used in obesity research, is a pancreatic lipase inhibitor that acts locally in the gastrointestinal tract to inhibit lipase.

Features and Benefits

This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Other Notes

Solution is not completely clear, small particles may remain floating.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c