Sigma-Aldrich Polycaprolactone. average Mn 80,000. 5 g

Name: Sigma-Aldrich Polycaprolactone. average Mn 80,000. 5 g
SKU: SIAL-440744-5G
Price: 80.39 USD

List Price $80.39 Your Price $80.39

Sigma-Aldrich Polycaprolactone. average Mn 80,000. 5 g - SIAL (Additional S&H Or Hazmat Fees May Apply)

NETA PART: SIAL-440744-5G

MFG.PART: 440744-5G

UNSPSC: 12352100

Manufacturer: Sigma-Aldrich

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Description

form

pellets (~3 mm)

mol wt

average M_n 80,000

greener alternative product characteristics

Design for Energy Efficiency
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

impurities

<0.5% water

mp

60 °C (lit.)

density

1.145 g/mL at 25 °C

M_W/M_n

application(s)

3D bioprinting
advanced drug delivery

greener alternative category

Enabling

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General description

Polycaprolactone (PCL) is a semi crystalline hydrophobic biodegradable polyester which finds major applications as a drug delivery agent because of its cost efficiency, high toughness and biocompatibility. PCL possesses some unique properties such as:

It degrades slower than other biodegradable polyesters in physiological condition, this property can be exploited in the controlled release of drugs in target tissues over a period of time.
Its poor surface wetting and interaction with biological fluids on account of its hydrophobicity leads to poor cell adhesion and proliferation, hence it is blended with other synthetic /natural polymers.[1]

We are committed to bringing you Greener Alternative Products, which belongs to one of the four categories of greener alternatives. This is an enabling product that belongs to a family of high-performance bio-based polymers that are essential for developing efficient, low-cost, and environmentally friendly renewable energy solutions. Click here for more information.

Application

PCL loaded with antibiotics may be used to treat infections of the respiratory tract, like tuberculosis.
Investigations were carried out based upon phenotypic responses of human bone marrow mesenchymal cells (hBMSCs) for different ratio of chitosan/ polycaprolactone (PCL) blends.[1]
PCL/biomedical ceramic materials have been studied for possible osteo tissue regeneration.
Action of PCL/graded insulin/beta-5 glycerophosphate concentrations on osteochondral tissue formation through adipose-derived stromal cell differentiation.[2]
Other general uses include:extrusion aid, die lubricant, mold release, pigment and filler dispersion aid and polyester segments in urethanes and block polyesters.

Features and Benefits

Biodegradable polymer
Non-toxic, biodegradable in soil, broad miscibility, mechanical compatibility with many polymers and good adhesion to a broad spectrum of substrates.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c