Sigma-Aldrich PalGly. ≥98% (HPLC), solid. 10 mg

Name: Sigma-Aldrich PalGly. ≥98% (HPLC), solid. 10 mg
SKU: SIAL-P0064-10MG
Price: 249.40 USD

List Price $249.40 Your Price $249.40

Sigma-Aldrich PalGly. ≥98% (HPLC), solid. 10 mg - SIAL (Additional S&H Or Hazmat Fees May Apply)

NETA PART: SIAL-P0064-10MG

MFG.PART: P0064-10MG

UNSPSC: 12352202

Manufacturer: Sigma-Aldrich

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Description

assay

≥98% (HPLC)

form

solid

color

white to off-white

solubility

DMSO: >10 mg/mL

storage temp.

2-8°C

SMILES string

O=C(CCCCCCCCCCCCCCC)NCC(O)=O

InChI

1S/C18H35NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-17(20)19-16-18(21)22/h2-16H2,1H3,(H,19,20)(H,21,22)

InChI key

KVTFEOAKFFQCCX-UHFFFAOYSA-N

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Biochem/physiol Actions

PalGly is an endogenous signaling lipid that modulates calcium influx and nitric oxide production.

PalGly is an endogenous signaling lipid that modulates calcium influx and nitric oxide production. PalGly inhibits heat-evoked firing of wide dynamic range (WDR) neurons, activates calcium influx in DRG cells and stimulates NO production. Preliminary studies suggest its signaling mechanism involves GPCR-mediated cation channel activation and a Gαi/o-coupled signaling pathway, which is being further investigated.

Features and Benefits

This compound is featured on the Nitric Oxide Synthases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c